best practice, its a safety measure that is expected when dealing with chemicals. Yes, you probably don't need it, but I don't know you well enough for assumptions to say that you won't pour it all over yourself or to pour the bottle of nicotine directly into mouth or eye.

I’m clumsy. I spill Nic on myself. Even at 48mg concentration (which I chose specifically because I’m clumsy) I’ve still gotten enough on my skin to cause a headache and slight nausea. I wear gloves now.

Depends.. some prefer the ability to be careless while mixing.

I prefer to be careful and rely on not pouring chemicals all over myself. It works as well... But then I could disarm mercury switches and such,. Others can't. You know yourself you know if you need safety equipment.

Just giving textbook definition when handling potential poisons and chemicals.

For a new mixer sure, rather make good mixers instead of bad practices, don't need someone failing and getting it in there eye or something and then coming back to sue someone like mcdonalds/coffee incident.

Less cleanup. No syringes or whatnot to clean. Just dump everything straight to the bottle. I used to use a syringe for my nicotine and cleaning it after every session is a pain. Now I use disposable pipettes

Pretty much what everyone else has said.

You can be way more accurate in your mixes. Some flavors are vastly different even in small measurements. syringes are for the most part accurate but it's incomparable to weight.

there's no problem with cross contamination. some flavors 'stain' plastics, so to speak. with mixing by weight you just use the bottle the flavor came in to dispense it into the bottle you're mixing in.

Mixing by weight is as simple as mixing inside the bottle you plan on filling your tank with.

Plus, buying new syringes can be eventually expensive. or at the very least it's an additional expense you can avoid entirely by mixing by weight.