There is an interesting research paper 'Electronic cigarettes: The nicotyrine hypothesis" that, in part, poses a theory of preferential bias toward nicotine-containing 'steeped' e-liquids due to the steeping process oxidizing nicotine to produce nicotyrine - a potent nicotine metabolizing enzyme inhibitor (cytochrome family CYP2A6 and CYP2A13). Nicotyrine inhibits the normal metabolic breakdown of nicotine (nicotine to cotinine to trans 3-hydroxycotinine) such that the overall effect of nicotyrine is to potentiate the effects of nicotine by inhibiting the above mentioned enzymes. Put simply, this means that vaping juice with oxidized nicotine (rich in nicotyrine) is more pleasing because less nicotine is required to placate withdrawal plus it has longer lasting effect, hence a perceived bias toward preferring 'steeped' ejuice.
Interested to hear what others think.
Interesting theory, but I feel it’s just a coincidence. What about steeping nicotine free ejuice? People still steep those. I think this is more of one of those data sets where 2 things line up for chemical reasons but not for human preference reasons. Steeping allows the flavors to oxidize/develop, resulting in the flavor people are looking for. Like others have said, creams and custards are steeped to produce the flavor. But I am shaking and vaping fruit flavors since they have their flavor pretty much right off the bat.
Also, here’s the thing..we smoked and loved it so naturally we love vaping! People want to quit dying from all the unnecessary chemicals and tar in cigarettes but we don’t necessarily want to quit smoking if that makes sense. I guarantee we would all still smoke if it didn’t kill us lol... and be so stanky haaa. My point is, we vapers also believe that nicotine is much less harmful than w thought before or BT would like u to still believe when vaping it. So, that’s why I don’t think ppl really care about how fast or how much nicotine is or isn’t being absorbed because as long as it is , is all that really matters and if it is a persons goal to be nicotine free, and there are definitely a percentage of ppl that are, then they just taper down and eventually get to that place and it’s not that hard. It was crazy easy to get to 3% for me and it wouldn’t be hard to get to 0 but I don’t want to. I like vaping and I’m not worried about nicotine in the slightest or anything else related to vaping. I feel like I’m cheating death even since I quit smoking and discovered vaping it’s really great!
I get your point re nicotine concerns - I'm not worried but it could matter in the long run because one of the hings that happens from nicotyrine is irreversible changes occur to one of the enzymes mentioned in the paper - that might have long term ramifications.
And like you I'm down to 0.75 % nicotine (100mg/ml) from 2% in less than twelve months, plus I just had a health check recently and found that I am now healthier than I was eight years ago! So I think vaping is pretty great too.
Did I understand you correctly and you said you don’t believe in steeping and have stopped because of personal experience and no scientific proof? I’m no scientist but I have learned from experience here that some flavors definitely need a steep, some don’t and some doesn’t matter. When creating a recipe there are several different flavors used is the problem you can’t use one rule...🤔 Kinda feel like this is noob shit. Anyway, as far as the nicotine, you can add the nicotine after the juice is steeped if u want, there’s also no rule about that. Talk about overwhelming a beginner thinking about whether or not to try vaping and he/she see’s this post they’re gonna run like hell imo 😂😩... I think it talks about things nobody ( avg vaper ) really cares about imo... I also didn’t know ppl didn’t want to be known as vapers. You mean they don’t mind being known as a smoker but vaping is somehow derrogatory? I question that fact. ...then the entire research is a little questionable. I’ll agree ppl still divided whether steeping is good or not but those are just the newest ones that haven’t given the due diligence to the process but as soon as each and every one does they immediately change their position and come to the steeping necessary side, so to me it’s not a question of preference at all it’s something you know when you finally do it lol...;) the end!
You misunderstood. What I said was, that for me personally, steeping doesn't do much except muddy my flavor mix so I tend to just let my mixes sit overnight, but I also said I don't think less of people who do steep. My question was and still is more related to how 'good' or 'better' are defined seeing as those are very subjective definitions that don't work for everyone.
I think what would be more likely to scare away beginners are phrases like "noob shit" and receiving hostile responses when specific topics or questions are asked.
The paper said nothing about being perceived as a vaper, but there is definitely (at least where I live) a certain negative stigma attached to vaping.
I'm well aware juices can change over time (nicotine or no nicotine) my question is more asking what makes it better and why, especially when you consider most flavorings can have many, often tens of, individual ingredients each.
There is nothing wrong with asking questions unless the answers you get are not the ones you want to hear nor are willing to consider :)
Kinda bogus.
Certain flavors need steeping to develop, some don't. I don't bother steeping lemonades more than overnight...
Kinda bogus how?
The preference for steeping or not is more a factor of the flavors used than any nicotine chemistry. One could argue the number of people vaping custards and creams rather than fruit flavors could be inflated by this chemistry trivia, but I don't think you'll find many people who prefer their citrus-based flavors steeped.
Well you can't argue with the science as it's not about steeping but investigating a more effective nicotine delivery method to help people quit smoking. Because many people who decide to quit and consider vaping find themselves quickly overwhelmed by the technicality, learning curve, lingo, best-practice, and so-on and so-on of vaping. I can understand this as I found it all a bit daunting to start with. Plus, many people do not want to be 'seen' by others as being a 'vaper' or part of what can easily be seen as a sub-culture. I can understand this too. The paper mentions that 1st and 2nd generation devices were more at efficient delivering nicotine (with less nicotyrine content) than compared with 3rd gen devices - how, I'm not sure, but suspect it has something to do with the highly airy vapor output content of modern devices.
I guess what I want to know is how can steeping be objectively proven to be better and how does one quantify 'better'? Ignoring the nicotyrine thing for a minute there are certainly minor flavor changes that do occur over time but I seriously question the majority held view that steeping is better because, to my knowledge, this has never been scientifically demonstrated to be either good or bad for flavor. It's a fair question, is it not?
Furthermore, I've looked into this in great depth and have found no convincing evidence; most reasons for steeping can be quite contradictory depending on who gives the answer and where it came from. I also find it odd that an internet search on this subject returns search results mostly before 2015-2016 and not much being found after that. This raises questions for me.
Personally, I find steeping any juice beyond several days to seriously muddy the flavors into one homogeneous 'blob' with very little layered separation so I just don't do it anymore, at least not intentionally. But that might just be me...
Considering flavor perception is so highly subjective I want to know that if steeping is truly beneficial for flavor how is that able to be objectively demonstrated other than by mass opinion.
And I don't knock anyone who does it, it just happens that I don't do it as I see no gain personally.
Hahaha. This aussie ass finally deleted.
I guess this means I don't need to review any of their recipes
Wow, what a welcoming community