A quote from the E-cigarette forums.
> They should make this a sticky because the newbies always ask this question. I'm a pharmacist in PA. I'm going to copy and paste a post I wrote in another subforum: > > Go to the skin care aisle of most any pharmacy and you'll find a small(usually 6oz) bottle labled Glycerine, USP(Some pharmacies don't carry outright , but will special order for you). The label may have it listed as CVS Glycerine, USP or Rite Aid Glycerine, USP or Humco Glycerine, USP or Family Pharmacy Glycerine, USP etc.. you get my point. Whatever it's labeled, it's Glycerine, USP 99.5% anhydrous(meaning 0.5% water). It will cost anywhere from $3 to $6 for 6oz.(CHEAP) This is vegetable glycerine, absolutely, positively, no doubt. How do I know this? I'm a pharmacist. All OTCglycerine,USP is made by 1 single manufacturer, HUMCO. It is then contract packaged into the different pharmacy labeled bottles. I've personally called HUMCO and spoke with their QA(quality assurance) person. He assured me that HUMCO's Glycerine is in fact Vegetable source Glycerine. The reason it's labeled Glycerine and not Vegetable Glycerine is because #1 it is listed in the USP as Glycerine, USP and therefore(in order to keep the USP certification) must be labeled as it's listed in the USP. #2 it would cause confusion as Glycerine is Glycerine(regardless of the source - chemically 1,2,3-propane triol also sometimes referred to as Glycerol), to add the moniker VEGETABLE, makes it sound like it's two different and distinct products, it isn't. Also, USP grade Glycerine is the purest you can get. Food Grade "vegetable Glycerine" you get in health food store saying 99.9% is BS. Since they do not have to meet any standard(such as USP standards) they could say anything, they could say 10000% pure. If you get USP grade, you know you are getting exactly what is labeled(within allowable USP limits) and it is made to most stringent requirements available in the US. (i.e. USP stands for United States Pharmacopeia- drugs have meet higher standards then foods do). Kashrut(kosher) laws are Jewish religious dietary laws having to do with the preparation of food products and really have nothing to do with the labeled purity of the product. Also, Kashrut(kosher) laws are jurisdictional(handled differently in different places). In some cases a rabbi must come to the manufacturer and verify processes and equipment conform to kosher law and in some places it's enough that the manufacturer says or thinks he is conforming to the kosher laws. In any case USP and Kosher are 2 different things. There is no such listing in the USP for "Kosher Glycerine". To the people who are feeling naseous using pharmacy bought Glycerine, USP, it may be a placebo effect(thinking your not using the real VG) or you may have a sensitivity to Glycerine(unlikely). But it is not because the Pharmacy bought Glycerine,USP is inferior or NOT Vegetable Glycerine.
The warning appears to be for children. I'm not a doctor, but it probably isn't a great idea for kids to fill their stomachs with this stuff.
Hey guys, im taking the step to start making my own e-juice but I have a quick question. I bought some vegetable glycerin, and this one was the only one the store had. Is this safe to use? Its USP grade 99% but the warning label has me kind of worried
They're just covering their ass' with the warning about consumption. most everything is harmful if consumed in large enough quantities. Even H2O can kill you if you drink to much.(Dilutional hyponatremia) Vape On Bro...
So can too much oxygen - quantities matter, go figure.
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####	 Oxygen toxicity:
>Oxygen toxicity is a condition resulting from the harmful effects of breathing molecular oxygen (O 2) at elevated partial pressures. It is also known as oxygen toxicity syndrome, oxygen intoxication, and oxygen poisoning. Historically, the central nervous system condition was called the Paul Bert effect, and the pulmonary condition the Lorrain Smith effect, after the researchers who pioneered its discovery and description in the late 19th century. Severe cases can result in [cell](https://en.wikipedia.org/wiki/Cell_(biology)) damage and death, with effects most often seen in the central nervous system, lungs and eyes. Oxygen toxicity is a concern for underwater divers, those on high concentrations of supplemental oxygen (particularly premature babies), and those undergoing hyperbaric oxygen therapy.
>====
^Interesting: ^Hyperoxia ^| ^Oxygen ^| ^List ^of ^signs ^and ^symptoms ^of ^diving ^disorders ^| ^Maximum ^operating ^depth
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Drinking glycerine will give you the shits*, but it's very unlikely to kill you; its LD50 is something on the order of 10 g/kg bw - meaning a 200 lb person has to ingest 2 lbs of the stuff to have even odds of dying.
* Glycerine is not strongly attacked by HCl or gut bacteria, so when it gets into your colon, it irritates your intestinal walls, causing your them to go hyperosmotic - that is, pull in moisture at an increased rate - loosening your stool. As a result, drinking enough glycerine will give you the squirts butt good. They use it in suppositories for this reason.
In the event of significant ingestion, the correct course of treatment is electrolyte replacement - because you're about to lose a lot of them pretty quickly, and that can kill you. Ain't nothing more embarrassing than shitting yourself to death.
Shouldn't be bad, but it isn't all created equal. I had a ~~allergic~~ reaction to the Humco stuff at Walmart. Made my mouth numb. I have no issues with the food grade glycerine at Whole Foods. I figured it should be comparable, but there is a difference. I haven't heard of a lot of people with that reaction, but know it is possible and they are not all the same.
> mouth numb
To explain your downvotes: Misinformation - This is not an allergic reaction.. Allergies do not "attack" one area over another. and you don't go "numb"
As someone with MANY food and environmental allergies I guarantee you that is not an allergic reaction. Burning inflammation, difficulty swallowing, and a highly sensitive/swollen mouth/throat/lung passage that would most likely require hospitalization .. Now that's an allergy.
> Made my mouth numb.
Er. There's a couple of possible explanations here.
First, this isn't a side effect of glycerine (Humco USP is purer than food grade), but it is a side effect of nicotine, clove oils, menthols, and a number of other aromatics. You may have gotten your mix a little off.
Second, food grade may have some water contamination - up to 5%, in many cases, and glycerine is strongly hydroscopic. The reaction you had may have been from the drying effect that results from using an anhydrous product - it feels a bit like numbing on mucous membranes, because the reduced moisture (masked by the "feel" of glycerine - it's funny stuff; both warming and a mix of oily and wet feeling) can also reduce nervous activation at the surface of the membranes. To test, premix 0.1 ml distilled water for every 0.9 ml of VG, then use that mix and see how it treats you.
Overall, if you're doing your own mixes, USP is what you want. Food grade and kosher stuff can be contaminated with heavy metals at higher rates than USP (USP has very, very strict rules around contamination; food grade and kosher, not so much).
Zero nic, only a couple flavors. Tried more than one mix with different flavors, thinking it was the PG ad I read about reactions to that. Stopped when I changed to Now VG from Whole Foods. Like I said, I'm not sure why, but it was enough to make me not want to vape those mixes.
Thank you very much guys I really appreciate the replies! Especially since this is a newbie question. You guys are great.
Just a suggestion...if you're going to do any amount of DIY moving forward, go to Amazon and get the big bottle of VG from essential depot for less than $13.
The stuff you're using is perfectly fine, but overpriced.
Yes it's 99.9% usp grade from Walmart to be extract, it's good
What about the warning label, why should poison control be called if ingested? Do all VGs have this?
See above. Short answer, it's a strong enough laxative that, should you drink enough, the resultant diarrhea would kill you from dehydration and electrolyte loss if you don't replace your fluids. If you call Poison Control, they will tell you how to deal with that.
But that's usually what PC is for anyway: to tell you how to avoid dying and getting very ill from ingesting non-foods. But yeah. The LD50 for glycerine itself is 10g/kg body weight. You'd have to drink a lot to die of metabolic consequences.
Anyone want to comment on the warning label or is it just a lawyer thing that has to be there?
I suspect it's a lawyer thing because on the front it says "An Emollient & Demulcent".
> Moisturizers or emollients are complex mixtures of chemical agents specially designed to make the external layers of the skin (epidermis) softer and more pliable...
> A demulcent (derived from the Latin: demulcere "caress") is an agent that supposedly forms a soothing film over a mucous membrane, relieving minor pain and inflammation of the membrane. Demulcents are sometimes referred to as mucoprotective agents.
I read that as external (emollient) and internal (demulcent). Since VG is used in medicines and foods designed to be taken orally, I wouldn't worry about it. Besides, you'd be inhaling instead of ingesting, right? :P
Maybe people have been known to drink a whole bottle prompting the warning.
ingesting means taking it into your body. If you snort it you would still be ingesting it.
in•gest
(ɪnˈdʒɛst)
v.t.
to take into the body, as food or liquid (opposed to egest).
[1610–20; < Latin ingestus, past participle of ingerere to heap on,
pour into the body =in- in-2 + gerere to carry]
in•gest′i•ble, adj.
in•ges′tion, n.
in•ges′tive, adj.
Generally, the word means to take in for digestion, by eating or drinking. Technically, it also means to absorb, and since you absorb things through the lungs, inhalation could be inferred. You can also ingest information but we don't see warnings about reading too many books.
I've used this quite a bit. I believe it's rebranded humco.
Can it be called rebranded if the word Humco is still there? Near the bottom on both pictures...
Haha, yeah I guess I didn't look very carefully, did I