Way easier for me. All my flavorings come in dropper bottles. Nothing to clean when I am done. No cost of replacing syringes. The only bad part is if you over shoot your target it's already in the bottle.

What mixing by weight is loads easier. just go straight from one bottle to another. No fucking around with pipettes/syringes. It's more accurate, consistent and convenient.

But with a scale you don't even have to use pipettes. Put the bottle on the scale, drip flavors directly into the bottle, add VG, put the cap on and you're done.

Mixing by volume will always have error, whether using disposable pipettes, graduated barrels, or even autopipettes. With a celebrated scale you can forego buying more expensive equipment and lower your error considerably.

Why even bother mixing by volume?

It's almost more of a hassle it seems. If you use syringes it seems mixing by weight is faster and cleaner. Unless I am missing something?

Because i mix 500ml at a time and syringes max out at 60ml

Place scale, throw bottle on it, squirt squirt squirt, done. No clean up of syringes, no nothing. Just shaking the juice and putting the caps back on.

I transfer all of my flavorings in to 1oz glass dropper bottles. My VG, PG, and nic are transferred to 8oz squeeze bottles so I can easily add it to my mixes. There's no waste, nothing to clean up, and I can make a 20ml batch in just a couple minutes and a 125ml batch in only a couple minutes more.

For recipe calculation I just use an Excel sheet where I have every flavor's specific gravity referenced for use in a formula to automatically adjust for my batch size.

I really don't think it could get any easier than this.

Current $17.99 
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What scale do you guys use?

I guess it depends if you mix big amounts or small. I do small so by weight is more a PIA than not.... Maybe if I ever get to big amounts, I may got the weight way.

What calculator are you guys using that gives you the weights?

Mixing by weight tends to be the preferred method for a variety of reasons. Notably, error rate to mixing drops dramatically (extra .01ml in a syringe, etc), consistency in mixing increases dramatically (always the same weight, always the same amount), and speed goes up when recreating a mix, with a minimal amount of lost time in the beginning for math.

Here's a better description of why I prefer weight over volume...
With mixing by volume, I need enough syringes available for each and every flavor, then I need to clean the syringes after. Not too bad, except that if you have 1.2ml of a flavor going into a 30ml bottles, and you load up for 1.0ml the first go around on your 1ml syringe, you're going to have some left over flavoring in the needle tip when you finish pushing in. Not bad, except that when you load up to 0.2 the next time around, your syringe will technically contain 0.25ml (fine, because the 0.05ml extra is from the 1.0ml). Now, you need to get all of that 0.25ml to have the perfect 1.2ml of flavoring. The only way I found to be consistent again and again with repeating my recipes was to use some PG to flush the remaining flavor out of the syringe (plus side, I can also reuse the syringe after this). It's a nuisance to have to flush the syringe to ensure I have the right amount of flavor. If I don't my levels will not be 100% consistent every time.

Now, with weight... I know I need the same 1.2ml of flavoring, so I grab a pipette. Now, assuming that I have a very heavy flavor, say, 1.06g/ml, I know I need 1.27g of flavoring, so I load up the pipette to wherever and put in a batch which comes to, say, 1.00g, well lets get some more flavor... same pipette, another 1/4th of what i had before, comes up at 1.22g... Mmm, add a few more drops and I'm at 1.27... Remaining flavor in the pipette goes into the flavoring bottle and I'm done, pipette is trashed. Nic, new pipette, repeat process above. PG and VG, I flip over a bottle that has a cut tip and pour to my hearts content, until I reach my levels I need. total time spent per bottle, maybe 2 minutes if I'm going slow and have the recipe math already done. 3 1/2 minutes if I take my time and have to look up a flavor or two...

But the kicker... If I want to repeat the above with volume on a 10ml because a friend wanted to try some, I cut the recipe into 1/3rd and start mixing. Now, what if I have an extra .05ml of something strong like a coconut in the bottle, because I forgot to flush as I was going, or because, well, syringes suck... The recipe is shot. But with weight, I cut into a 1/3rd value and I end up with .42 flavoring, I wont be making any mistakes... I wont have any extra, or be missing some, because it's 0.42.

Now for time... Mixing up with syringes took me about 5 minutes per bottle with VG. VG is the devil with syringes. With weight, I have both PG and VG in bottles that have dropper tops on them and I just squeeze until I am where I need to be. I cut the 1 minute time suck of VG on larger batches into seconds, I cut the 30 second time suck of PG into seconds. Repeat with flavors and Nic (neither take much time if you just put flavors in all willy nilly and dont flush to ensure accuracy), I still do those in half the time or better. 2 minutes with weight, including clean up, versus 5 minutes with syringes, without clean up.

Comes down to how you value your time. I like being able to mix up 4 new recipes in the time it took to do 2 before. I also like being able to walk away without having to clean up any syringes or do much else besides enjoy the bottle I just mixed. Now I want to to mix something. Damn.

I do see the advantages of mixing by weight, but I think folks should keep in mind that not all flavorings come with droppers. I'm using stuff from Wizard Labs, and although I could get droppers for them, their 8ml flavoring vials don't come with any.

I think mixing by weight is most useful when you mix more complicated recipes in the bottle regularly. When I'm making flavor tests, cleaning one syringe per bottle isn't too bad. And when mixing 500ml+ at once, cleaning several syringes still isn't much overhead.

TFA has msds sheets with the weights on it for their flavors. If you can't find a msds then weigh your flavor @ 1 ml 3 times and get the correct weight for it. Once you have the weight for all your flavors your mixing time will be cut by at least half and there is no clean up.

There is a post with weights for a lot of flavors here in the diy section that will give you a head start on building your info. I also have a lot of weights but need to pull them all together in a spreadsheet.

Weight mixer here. I use the "Liquix" calculator for Android which converts MLs and percentages listed for the recipe into grams. Since all my flavors are in bottles with dropper tips all I need to is drip the exact amount required by the recipe into the new-batch bottle, resetting the scale (TARE) in between flavors. It works pretty much flawlessly, is stupidly accurate and I never even touch a syringe or pipette. Unless you have some automated machine, then mixing by weight simply CANNOT get easier.

Do you put all your flavors into new bottles with droppers? Or they come like that?

I use glass transfer pipettes, they are great and always easily cleaned